RGR Rabbit Polyclonal Antibody

CAT#: TA358414

RGR Antibody - N-terminal region

Product Images

WB Suggested Anti-RGR Antibody Titration: 1.0 ug/ml Positive Control: PANC1 Whole CellRGR is supported by BioGPS gene expression data to be expressed in PANC1

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish
  Homology: Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 100%; Rat: 86%; Zebrafish: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 32kDa
• Gene Name: retinal G protein coupled receptor
• Database Link:
  NP_002912
  Entrez Gene 5995 Human
  UniProt ID P47804-2
• Background: This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).
• Synonyms: RGR-opsin; RP44

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane