Cyclin B2 (CCNB2) Rabbit Polyclonal Antibody

CAT#: TA358424

CCNB2 Antibody - C-terminal region

Product Images

WB Suggested Anti-CCNB2 Antibody Titration: 1.0 ug/ml Positive Control: NCI-H226 Whole CellCCNB2 is supported by BioGPS gene expression data to be expressed in NCIH226

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  Lanes: Lane1: 40 ug human HCT116 cell lysate Lane2: 40 ug 1mM hydroxyurea treated HCT116 cell lysate Lane3: 40 ug 10uM Etoposide treated human HCT116 cell lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:5000 Gene Name: CCNB2 Submitted by: Claudia Schafer & Dr. Oliver Kramer, Institute for Biochemistry and Biophysics, Center for Molecular Biomedicine, Friedrich-Schiller University Jena CCNB2 is supported by BioGPS gene expression data to be expressed in HCT116

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 44kDa
• Gene Name: cyclin B2
• Database Link:
  NP_004692
  Entrez Gene 9133 Human
  UniProt ID O95067
• Background: Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
• Synonyms: HsT17299

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Cell cycle, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation