THEMIS Rabbit Polyclonal Antibody

CAT#: TA358535

THEMIS Antibody - C-terminal region

Product Images

WB Suggested Anti-THEMIS Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 66kDa
• Gene Name: thymocyte selection associated
• Database Link:
  NP_001158159
  Entrez Gene 387357 Human
  UniProt ID Q8N1K5
• Background: THEMIS plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. It is required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. It regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
• Synonyms: bA325O24.3; bA325O24.4; C6orf190; C6orf207; FLJ40584; MGC163388; TSEPA