IL1RAPL1 Rabbit Polyclonal Antibody

CAT#: TA359412

IL1RAPL1 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: IRPL1 Sample Type: Fetal Kidney lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IRPL1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 76kDa
• Gene Name: interleukin 1 receptor accessory protein like 1
• Database Link:
  XP_005274498
  Entrez Gene 11141 Human
  UniProt ID Q9NZN1
• Background: The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization.
• Synonyms: IL1R8; IL1RAPL; IL1RAPL-1; MRX10; MRX21; MRX34; oligophrenin-4; OPHN4; OTTHUMP00000023097; TIGIRR-2