LILRB4 Rabbit Polyclonal Antibody

CAT#: TA359460

LILRB4 Antibody - C-terminal region

Product Images

WB Suggested Anti-LIRB4 antibody Titration: 1 ug/mL Sample Type: Human OVCAR-3 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-LILRB4 antibody is: synthetic peptide directed towards the C-terminal region of Human LIRB4
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 49 kDa
• Gene Name: leukocyte immunoglobulin like receptor B4
• Database Link:
  Entrez Gene 11006 Human
  UniProt ID Q8NHJ6
• Background: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CD85K; HM18; ILT-3; ILT3; LILRB5; LIR-5; LIR5; OTTHUMP00000068605