MTRR Rabbit Polyclonal Antibody

CAT#: TA359469

MTRR Antibody - middle region

Product Images

Host: Rabbit Target Name: MTRR Sample Type: Hela Whole Cell lysates Antibody Dilution: 1.0ug/ml

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  WB Suggested Anti-MTRR antibody Titration: 1 ug/mL Sample Type: Human liver

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  Rabbit Anti-MTRR Antibody Catalog Number: TA359469 Formalin Fixed Paraffin Embedded Tissue: Human Adult liver Observed Staining: Membrane Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data.

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MTRR
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 76kDa
• Gene Name: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
• Database Link:
  Entrez Gene 4552 Human
  UniProt ID Q9UBK8-2
• Background: Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
• Synonyms: cblE; MGC129643; MSR