TGF beta Receptor I (TGFBR1) Rabbit Polyclonal Antibody

CAT#: TA362492

TGFBR1 Antibody - middle region

Product Images

Host: Rabbit Target Name: TGFBR1 Sample Tissue: Human HT1080 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human TGFBR1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 55 kDa
• Gene Name: transforming growth factor beta receptor 1
• Database Link:
  NP_001124388.1
  Entrez Gene 7046 Human
  UniProt ID P36897
• Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: AAT5; ACVRLK4; ALK-5; ALK5; LDS1A; LDS2A; SKR4; TbetaR-I; TGFR-1