p53R2 (RRM2B) Rabbit Polyclonal Antibody

CAT#: TA362635

RRM2B Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: RRM2B Sample Tissue: Human 786-0 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RRM2B
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 32 kDa
• Gene Name: ribonucleotide reductase regulatory TP53 inducible subunit M2B
• Database Link:
  NP_001165948.1
  Entrez Gene 50484 Human
  UniProt ID Q7LG56-2
• Background: This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
• Synonyms: DKFZp686M05248; MGC42116; MGC102856; p53R2; PEOA5