Hey2 Rabbit Polyclonal Antibody

CAT#: TA362980

HEY2 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: HEY2 Sample Tissue: Mouse Spleen lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse HEY2
• Specificity: Expected reactivity: Mouse
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 35 kDa
• Gene Name: hairy/enhancer-of-split related with YRPW motif 2
• Database Link:
  NP_038932.1
  Entrez Gene 15214 Mouse
  UniProt ID Q9DBX7
• Background: Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3' (By similarity). Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
• Synonyms: bHLHb32; CHF1; GRIDLOCK; GRL; hCHF1; HERP; HERP1; HESR-2; HESR2; hHRT2; HRT2; MGC10720