HINT2 Rabbit Polyclonal Antibody
Other products for "HINT2"
Specifications
Product Data | |
Applications | ELISA, IHC |
Recommended Dilution | IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human HINT2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Database Link | |
Background | Hint2 (histidine triad nucleotide binding protein 2), also known as HIT-17, is a 163 amino acid secreted protein that contains one HIT domain, a histidine triad that has catalytic activity toward the å-phosphate of ribonucleotides. Via its HIT domain, Hint2 is thought to function as a hydrolase that is encoded by a gene which maps to chromosome 9. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia and Familial dysautonomia are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. |
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