TGFBI Rabbit Polyclonal Antibody

CAT#: TA364564

TGFBI rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: 293T cell lysate Primary antibody: TA364564 (TGFBI Antibody) at dilution 1/1050 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 30 seconds

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA364564 (TGFBI Antibody) at dilution 1/75 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA364564 (TGFBI Antibody) at dilution 1/75, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T cell lysate
  IHC: 50-200
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human TGFBI
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 75 kDa
• Database Link:
  UniProt ID Q15582
• Background: This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.