TNIK Rabbit Polyclonal Antibody

CAT#: TA367616

TNIK rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human brain tissue using TA367616 (TNIK Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA367616 (TNIK Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA367616 (TNIK Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA367616 (TNIK Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human brain
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TNIK
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Database Link:
  UniProt ID Q9UKE5
• Background: TNIK (TRAF2 and NCK-interacting protein kinase) is a 1,360 amino acid protein that contains one protein kinase domain and belongs to a subfamily of Ser/Thr protein kinases. Expressed ubiquitously with highest expression in brain, heart and skeletal muscle, TNIK functions as a stress-activated Ser/Thr kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to play a role in the response to environmental stress. Additionally, via its catalytic activity, TNIK may participate in cytoskeletal regulation events throughout the cell. TNIK exists as 8 isoforms that are produced by alternative splicing events.