DDX43 Rabbit Polyclonal Antibody
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Other products for "DDX43"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 200-1000 WB positive control: HepG2 cells IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm or Nucleus |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Fusion protein of human DDX43 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Predicted Protein Size | 73 kDa |
Database Link | |
Background | DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis. |
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