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CHIT1 Rabbit Polyclonal Antibody
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Other products for "CHIT1"
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommended Dilution | WB: 200-1000 WB positive control: Human spleen tissue and Human lung tissue lysates IHC: 25-100 Positive control: Human gastric cancer Predicted cell location: Cytoplasm and Cell membrane |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human CHIT1 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Predicted Protein Size | 52 kDa |
| Database Link | |
| Background | Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. |
| Reference Data | |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.