PAK3 Rabbit Polyclonal Antibody

CAT#: TA371189

PAK3 rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-2: Human fetal brain tissue Mouse brain tissue Primary antibody: TA371189 (PAK3 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human fetal brain and Mouse brain tissue
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PAK3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 62 kDa
• Gene Name: p21 (RAC1) activated kinase 3
• Database Link:
  Entrez Gene 5063 Human
  UniProt ID O75914
• Background: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets.
• Synonyms: beta-PAK; bPAK; CDKN1A; hPAK3; MRX30; MRX47; Oligophrenin-3; OPHN3; OTTHUMP00000023856; PAK-3; PAK3beta