Ryanodine Receptor (RYR1) Rabbit Polyclonal Antibody
Other products for "RYR1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 200-1000 WB positive control: Mouse brain tissue |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human RYR1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Predicted Protein Size | 565 kDa |
Gene Name | ryanodine receptor 1 |
Database Link | |
Background | This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. |
Synonyms | CCO; MHS; MHS1; RYDR; RYR; RYR-1; SKRR |
Reference Data |
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