MEK7 (MAP2K7) Rabbit Polyclonal Antibody
Other products for "MAP2K7"
Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | IHC: 20-100 Positive control: Human colorectal cancer Predicted cell location: Cytoplasm |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MAP2K7 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C. |
Stability | 1 year |
Gene Name | mitogen-activated protein kinase kinase 7 |
Database Link | |
Background | The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. |
Synonyms | Jnkk2; MAPKK7; MEK7; MKK7; PRKMK7 |
Reference Data |
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