Cytokeratin 14 (KRT14) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB,1:500 - 1:2000 IHC,1:50 - 1:100 IF,1:50 - 1:100 |
Reactivities | Human, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human Cytokeratin 14 (Cytokeratin 14 (KRT14)) (NP_000517.2). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 51kDa |
Gene Name | keratin 14 |
Database Link | |
Background | This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. |
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