PDE6 gamma (PDE6G) Rabbit Polyclonal Antibody

CAT#: TA379738

PDE6G Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using PDE6G antibody (TA379738) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit .|Exposure time: 30s.

• 

  Immunofluorescence analysis of C6 cells using PDE6G antibody (TA379738) at dilution of 1:100. Blue: DAPI for nuclear staining.

• 

  Immunofluorescence analysis of L929 cells using PDE6G antibody (TA379738) at dilution of 1:100. Blue: DAPI for nuclear staining.

• 

  Immunofluorescence analysis of U-2 OS cells using PDE6G antibody (TA379738) at dilution of 1:100. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB,1:500 - 1:2000
  IF,1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-87 of human PDE6G (NP_002593.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Gene Name: phosphodiesterase 6G
• Database Link:
  Entrez Gene 5148 Human
  UniProt ID P18545
• Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
• Synonyms: DKFZp686C0587; MGC125749; PDEG