EAAT4 (SLC1A6) Rabbit Polyclonal Antibody

CAT#: TA381571

SLC1A6 Rabbit polyclonal Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:500 - 1:1000
• Reactivities: Human, Mouse
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 155-265 of human SLC1A6 (NP_001259016.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 34kDa/61kDa
• Gene Name: solute carrier family 1 member 6
• Database Link:
  Entrez Gene 6511 Human
  UniProt ID P48664
• Background: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Functions as a symporter that transports one amino acid molecule together with two or three Na(+ ions and one proton, in parallel with the counter-transport of one K(+ ion. Mediates Cl(- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+ symport (By similarity. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (Probable.