APPL (APPL1) Rabbit Monoclonal Antibody [Clone ID: R05-8D5]

CAT#: TA383744

APPL Rabbit monoclonal Antibody

Product Images

Western blot detection of APPL in Rat Brain,C6,3T3,Hela cell lysates using APPL Rabbit mAb(1:1000 diluted).Predicted band size:80kDa.Observed band size:80kDa.

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  Immunohistochemistry of APPL in paraffin-embedded Human lung cancer tissue using APPL Rabbit mAb at dilution 1/20

Specifications

Product Data

• Clone Name: R05-8D5
• Applications: IHC, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human APPL
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 80 kDa; Observed MW: 80 kDa
• Gene Name: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
• Database Link:
  Entrez Gene 26060 Human
  UniProt ID Q9UKG1
• Background: Swiss-Prot Acc.Q9UKG1.Adapter protein that interacts with proteins involved in different cellular signaling pathways. Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction. Involved in the regulation of the insulin receptor signaling pathway.
• Synonyms: APPL; Dip13-alpha; DIP13A; DIP13alpha; KIAA1428