CAMK2A Rabbit Monoclonal Antibody [Clone ID: R09-9E5]

CAT#: TA383856

CaMKII alpha Rabbit monoclonal Antibody

Product Images

Western blot detection of CaMKII alpha in Rat Brain,Hela cell lysates using CaMKII alpha Rabbit mAb(1:1000 diluted).Predicted band size:54kDa.Observed band size:54kDa.

Specifications

Product Data

• Clone Name: R09-9E5
• Applications: WB
• Recommended Dilution: WB: 1/1000-1/2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human CaMKII
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 54 kDa; Observed MW: 54 kDa
• Gene Name: calcium/calmodulin dependent protein kinase II alpha
• Database Link:
  Entrez Gene 815 Human
  UniProt ID Q9UQM7
• Background: Swiss-Prot Acc.Q9UQM7.Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission . Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378).
• Synonyms: CAMKA; CaMKIINalpha; KIAA0968