Caspase 10 (CASP10) Rabbit Monoclonal Antibody [Clone ID: R03-2J3]

CAT#: TA383871

Caspase 10 Rabbit monoclonal Antibody

Product Images

Western blot detection of Caspase 10 in K562 cell lysates using Caspase 10 Rabbit mAb(1:1000 diluted).Predicted band size:59kDa.Observed band size:59kDa.

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  Immunohistochemistry of Caspase-10 in paraffin-embedded Human lung cancer tissue using Caspase-10 Rabbit mAb at dilution 1/20

Specifications

Product Data

• Clone Name: R03-2J3
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/2000
  IHC: 1/20
  IP: 1/20
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human Caspase-10
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 59 kDa; Observed MW: 59 kDa
• Gene Name: caspase 10
• Database Link:
  Entrez Gene 843 Human
  UniProt ID Q92851
• Background: Swiss-Prot Acc.Q92851.Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
• Synonyms: ALPS2; CASP-10; FLICE2; MCH4