CNGB1 Rabbit Polyclonal Antibody

CAT#: TA384019

CNGB1 Rabbit polyclonal Antibody

Product Images

Western Blot analysis of various cells using CNG-1β Polyclonal Antibody

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  Western Blot analysis of 3T3 cells using CNG-1β Polyclonal Antibody

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  Western blot analysis of lysates from NIH/3T3 and A549 cells, using CNGB1 Antibody. The lane on the right is blocked with the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 1/500-1/2000
  ELISA: 1/10000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human CNGB1. AA range:571-620
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):102
• Database Link:
  UniProt ID Q14028
• Background: Swiss-Prot Acc.Q14028.Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP.Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties: it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit.SitesFeature keyPosition(s)Description