EGFR Rabbit Polyclonal Antibody

CAT#: TA384136

Phospho-EGFR (Tyr845) Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of A549 cells, untreated or EGF-stimulated, using Phospho-EGF Receptor (Tyr845) Rabbit pAb (upper,1:500 diluted) and EGF Receptor Antibody 201012-6H11 (lower,1:500 diluted).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1/500
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CGAEEKEp-YHAEGGK (Phosphorylated)
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 175kDa
• Gene Name: epidermal growth factor receptor
• Database Link:
  Entrez Gene 1956 Human
  UniProt ID P00533
• Background: Swiss-Prot Acc.P00533.EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
• Synonyms: ERBB; ERBB1; HER1; mENA; PIG61