Eph receptor B1 (EPHB1) Mouse Monoclonal Antibody [Clone ID: 9B4-3F8-1H5]

CAT#: TA384183

Ephrin Receptor B1 (9B4) Mouse monoclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and colon cancer (right) showing cytoplasmic localization with DAB staining using EphB1 mouse mAb.

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  Western blot analysis using EhpB1 mouse mAb against MDA-MB-468 (1), MDA-MB-453 (2), MCF-7 (3), T47D (4) and SKBR-3 (5) cell lysate.

Specifications

Product Data

• Clone Name: 9B4-3F8-1H5
• Applications: IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/200-1/1000
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant fragment of EphB1 (aa19-133) expressed in E. Coli.
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Ascitic Fluid
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 110kDa
• Gene Name: EPH receptor B1
• Database Link:
  Entrez Gene 2047 Human
  UniProt ID P54762
• Background: Swiss-Prot Acc.P54762.EhpB1: EPH receptor B1. It is a receptor for ephrin-B family members. Ephrin receptors and their ligands, the ephrins, medate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.
• Synonyms: ELK; EPHT2; FLJ37986; Hek6; NET