Fadd Rabbit Monoclonal Antibody [Clone ID: R05-1K1]

CAT#: TA384205

FADD Rabbit monoclonal Antibody

Product Images

Western blot detection of FADD in SHSY-5Y cell lysates using FADD Rabbit mAb(1:1000 diluted).Predicted band size:23KDa.Observed band size:28KDa.

Specifications

Product Data

• Clone Name: R05-1K1
• Applications: IHC, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20-1/50
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of mouse FADD
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 23 kDa; Observed MW: 28 kDa
• Gene Name: Fas (TNFRSF6)-associated via death domain
• Database Link:
  Entrez Gene 14082 Mouse
  UniProt ID Q61160
• Background: Swiss-Prot Acc.Q61160.Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling .
• Synonyms: GIG3; MGC8528; MORT1