FBP1 Rabbit Monoclonal Antibody [Clone ID: R04-1D6]

CAT#: TA384213

FBP1 Rabbit monoclonal Antibody

Product Images

Western blot detection of FBP1 in Rat Brain lysates using FBP1 Rabbit mAb(1:1000 diluted).Predicted band size:37kDa.Observed band size:37kDa.

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  Immunohistochemistry of FBP1 in paraffin-embedded Human lung cancer tissue using FBP1 Rabbit mAb at dilution 1/20

Specifications

Product Data

• Clone Name: R04-1D6
• Applications: IHC, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20-1/50
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human FBP1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 37 kDa; Observed MW: 37 kDa
• Gene Name: fructose-bisphosphatase 1
• Database Link:
  Entrez Gene 2203 Human
  UniProt ID P09467
• Background: Swiss-Prot Acc.P09467.Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
• Synonyms: FBP