H2A.Z (H2AFZ) Rabbit Monoclonal Antibody [Clone ID: R09-3H9]

CAT#: TA384366

Histone H2A.Z Rabbit monoclonal Antibody

Product Images

Western blot detection of Histone H2A.Z in K562,C6,3T3 cell lysates using Histone H2A.Z Rabbit mAb(1:1000 diluted).Predicted band size:14kDa.Observed band size:14kDa.

Specifications

Product Data

• Clone Name: R09-3H9
• Applications: WB
• Recommended Dilution: WB: 1/1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Histone H2A.Z
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 14 kDa; Observed MW: 14 kDa
• Gene Name: H2A histone family member Z
• Database Link:
  Entrez Gene 3015 Human
  UniProt ID P0C0S5
• Background: Swiss-Prot Acc.P0C0S5.Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
• Synonyms: H2A.z; H2A/z; H2AZ; MGC117173