HDAC8 Rabbit Polyclonal Antibody

CAT#: TA384403

HDAC8 Rabbit polyclonal Antibody

Product Images

Western blot analysis of HDAC8 expression in HeLa cell lysate.

Specifications

Product Data

• Applications: FC, IP, WB
• Recommended Dilution: WB: 1/1000
  IP: 1/50
  FC: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human HDAC8
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 42kDa
• Gene Name: histone deacetylase 8
• Database Link:
  Entrez Gene 55869 Human
  UniProt ID Q9BY41
• Background: Swiss-Prot Acc.Q9BY41.Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. May play a role in smooth muscle cell contractility.
• Synonyms: CDA07; HD8; HDACL1; RPD3