HTRA2 Mouse Monoclonal Antibody [Clone ID: 8G11-4B8-4F10-G5]

CAT#: TA384476

HtrA2 (8G11) Mouse monoclonal Antibody

Product Images

Western blot detection of HtrA2/Omi in 293T cell lysates using HtrA2/Omi mouse mAb(dilution 1:500).Predicted band size:49kDa.Observed band size:36kDa.

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  Immunoprecipitation analysis of Hela cell lysates using HtrA2/Omi mouse mAb.

Specifications

Product Data

• Clone Name: 8G11-4B8-4F10-G5
• Applications: IP, WB
• Recommended Dilution: WB: 1/500
  IP: 1/20
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human HtrA2/Omi protein.
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa): 37
• Gene Name: HtrA serine peptidase 2
• Database Link:
  Entrez Gene 27429 Human
  UniProt ID O43464
• Background: Swiss-Prot Acc.O43464.High temperature requirement protein A2 (HtrA2)/Omi is a serine protease with homology to the E. coli HtrA protein (DegP) and is thought to be involved in apoptosis and stress-induced degradation of misfolded proteins. While HtrA2 was orignally identified to be present in either the nucleus or endoplasmic reticulum, subsequent studies have shown that it localizes in mitochondria and is released during apoptosis.
• Synonyms: OMI; PARK13; PRSS25