IFNAR1 Rabbit Polyclonal Antibody
Other products for "IFNAR1"
Specifications
Product Data | |
Applications | FC, IP, WB |
Recommended Dilution | WB: 1/500-1/2000 IP: 1/50 FC: 1/50 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human IFNAR1 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | 90,130kDa |
Gene Name | interferon alpha and beta receptor subunit 1 |
Database Link | |
Background | Swiss-Prot Acc.P17181.Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. |
Synonyms | AVP; IFN-alpha-REC; IFNAR; IFNBR; IFRC |
Reference Data |
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