IKB beta (NFKBIB) Mouse Monoclonal Antibody [Clone ID: 5H3-4C7-1H6]

CAT#: TA384867

IKB beta (5H3) Mouse monoclonal Antibody

Specifications

Product Data

• Clone Name: 5H3-4C7-1H6
• Applications: IHC
• Recommended Dilution: IHC: 1/100-200
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant protein expressed in E.coli.
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 48kDa
• Gene Name: NFKB inhibitor beta
• Database Link:
  Entrez Gene 4793 Human
  UniProt ID Q15653
• Background: Swiss-Prot Acc.Q15653.Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
• Synonyms: I-kappa-B-beta; IkappaBbeta; IkB-B; IkB-beta; IKBB; NF-kappa-BIB; TRIP-9; TRIP9