PSMA4 Rabbit Monoclonal Antibody [Clone ID: R08-8H3]

CAT#: TA385064

PSMA4 Rabbit monoclonal Antibody

Product Images

Western blot detection of PSMA4 in K562,C6,3T3,Hela cell lysates using PSMA4 Rabbit mAb(1:1000 diluted).Predicted band size:30kDa.Observed band size:30kDa.

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  Immunohistochemistry of PSMA4 in paraffin-embedded Human tonsil using PSMA4 Rabbit mAb at dilution 1/50

Specifications

Product Data

• Clone Name: R08-8H3
• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/100
  ICC/IF: 1/100
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human PSMA4
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 30 kDa; Observed MW: 30 kDa
• Gene Name: proteasome subunit alpha 4
• Database Link:
  Entrez Gene 5685 Human
  UniProt ID P25789
• Background: Swiss-Prot Acc.P25789.Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
• Synonyms: HC9; HsT17706; MGC12467; MGC24813; MGC111191; PSC9