RASSF1 Rabbit Polyclonal Antibody

CAT#: TA385134

RASSF1 Rabbit polyclonal Antibody

Product Images

Western blot analysis of RASSF1 expression in HeLa cell lysate.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human RASSF1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 39kDa
• Gene Name: Ras association domain family member 1
• Database Link:
  Entrez Gene 11186 Human
  UniProt ID Q9NS23
• Background: Swiss-Prot Acc.Q9NS23.Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
• Synonyms: 123F2; NORE2A; RASSF1A; RDA32; REH3P21; WUGSC:H_LUCA12.5