TRIM25 Rabbit Polyclonal Antibody

CAT#: TA385463

TRIM25 Rabbit polyclonal Antibody

Product Images

Western blot analysis of TRIM25 expression in HeLa cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/50-1/200
  ICC/IF: 1/100-1/500
  IP: 1/50
  FC: 1/60
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human TRIM25
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 71kDa
• Gene Name: tripartite motif containing 25
• Database Link:
  Entrez Gene 7706 Human
  UniProt ID Q14258
• Background: Swiss-Prot Acc.Q14258.Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.
• Synonyms: EFP; RNF147; Z147; ZNF147