RAP80 (UIMC1) Rabbit Polyclonal Antibody
Other products for "UIMC1"
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB: 1/1000-1/5000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human RAP80 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | 80kDa |
Gene Name | ubiquitin interaction motif containing 1 |
Database Link | |
Background | Swiss-Prot Acc.Q96RL1.Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). |
Synonyms | RAP80; RXRIP110; X2HRIP110 |
Reference Data |
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