Cr2 Rabbit Monoclonal Antibody [Clone ID: 7G6]

CAT#: TA385833

Recombinant Anti-Complement Receptor 1 & 2 (Clone 7G6)

Product Images

Flow-cytometry using anti-complement receptors 1 & 2 antibody 7G6 (Ab00236) Mouse lymphocytes were stained with an isotype control (Ab00102-23.0, panel A) or the rabbit-chimeric version of 7G6 (TA385833, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FACSCanto flow-cytometer.

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  Immunohistochemical staining of rat stomach using anti-Complement receptors 1&2 antibody TA385833 Formalin fixed rat stomach slices were were stained with TA385833 at 3 µg/ml.

Specifications

Product Data

• Clone Name: 7G6
• Applications: FC, IHC, IP, WB
• Reactivities: Mouse
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: Purified Mouse CR1.
• Specificity: Recognises an epitope shared by 145-150kDa and 190kDa complement receptor proteins, originally designated CR2 (CD21) and CR1 (CD35).
  
  This antibody binds mouse complement receptors CR1 and CR2, functionally blocking CR2 leading to suppression of a normal antibody immune response (see Heyman et al. 1990, PMID: 1695671)
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: complement receptor 2
• Database Link:
  Entrez Gene 12902 Mouse
  UniProt ID P19070
• Synonyms: C3DR; CD21; SLEB9