GPR119 Mouse Monoclonal Antibody [Clone ID: Gipg013]

CAT#: TA385946

Recombinant Anti-Glucose-dependent insulinotropic Receptor (Clone Gipg013)

Specifications

Product Data

• Clone Name: Gipg013
• Applications: Bl, ELISA, IF
• Reactivities: Human, Mouse, Rat, Dog
• Modifications: This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
• Host: Mouse
• Isotype: IgG2a, lambda
• Clonality: Monoclonal
• Immunogen: Human GIPr.
• Specificity: The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.
  
  This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81%.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: G protein-coupled receptor 119
• Database Link:
  Entrez Gene 139760 Human
  UniProt ID Q8TDV5
• Synonyms: Gpr119