GPR119 Mouse Monoclonal Antibody [Clone ID: Gipg013]

CAT#: TA385946

Recombinant Anti-Glucose-dependent insulinotropic Receptor (Clone Gipg013)


USD 523.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Clone Name Gipg013
Applications Bl, ELISA, IF
Reactivities Human, Mouse, Rat, Dog
Modifications This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
Host Mouse
Isotype IgG2a, lambda
Clonality Monoclonal
Immunogen Human GIPr.
Specificity The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.

This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81%.
Formulation PBS with 0.02% Proclin 300.
Concentration lot specific
Conjugation Unconjugated
Storage Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Stability 3 years from dispatch.
Gene Name G protein-coupled receptor 119
Synonyms Gpr119
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.