TRAC Rabbit Monoclonal Antibody [Clone ID: 34]

CAT#: TA385994

Recombinant Anti-Vα TCR (Clone 34)

Specifications

Product Data

• Clone Name: 34
• Applications: ELISA, FC, WB
• Reactivities: Human
• Modifications: This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: Purified recombinant soluble TCR from the T-cell hybridoma 85.33, corresponding to V alpha 11
• Specificity: This antibody binds to the T-cell receptor alpha chains.
  
  The antibody binds specifically to the recombinant and native variable domain of the α chain which comprises the T-cell receptor (TCR). The TCR is a disulfide-linked heterodimeric protein expressed on the surface of T-cells in complex with CD3 and ζ-chain molecules. The receptor functions in the recognition of MHC molecule and the subsequent activation of T-cells. The monoclonal antibody 34 recognises Vα regions of TCRs expressed in the 85.33 arthritogenic T-cell hybridoma and can be used to analyse TCR V gene expression and for immunotherapy in T cell mediated autoimmunity.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: T-cell receptor alpha constant
• Database Link:
  Entrez Gene 28755 Human
  UniProt ID P01848