Integrin alpha 4 (ITGA4) Mouse Monoclonal Antibody [Clone ID: Natalizumab]

CAT#: TA386069

Recombinant Anti-Integrin alpha 4 (Clone Natalizumab)

Specifications

Product Data

• Clone Name: Natalizumab
• Applications: FC
• Reactivities: Human
• Modifications: This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
• Specificity: This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
  
  This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: integrin subunit alpha 4
• Database Link:
  Entrez Gene 3676 Human
  UniProt ID P13612
• Synonyms: CD49D; IA4; MGC90518; VLA-4