CD47 Rat Monoclonal Antibody [Clone ID: mIAP430]

CAT#: TA386094

Recombinant Anti-CD47 (Clone mIAP430)

Specifications

Product Data

• Clone Name: mIAP430
• Applications: Bl, IF
• Reactivities: Human
• Host: Rat
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: This antibody was raised by immunising IAP-deficient mice with purified human placental CD47.
• Specificity: This antibody recognises CD47 which is a a multitransmembrane glycoprotein widely expressed on all hematopoietic cells and most other cell types. It is involved in cell adhesion, Ca2+ influx, platelet activation and peripheral mononuclear neutrophils migration across endothelial and epithelial monolayers.
  
  This antibody can be used to investigate the role of the CD47 receptor. mIAP430 was first used to visualise the distribution of CD47 on fusing macrophages (Han et al., 2000). Further, it was demonstrated that this antibody can block fusion of macrophages by blocking CD47 and preventing the binding of this receptor with MFR (Han et al., 2000).
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: CD47 molecule
• Database Link:
  Entrez Gene 961 Human
  UniProt ID Q08722
• Synonyms: IAP; MER6; OA3