Csf1r Rat Monoclonal Antibody [Clone ID: AFS98]

CAT#: TA386345

Recombinant Anti-CD115/M-CSFR (Clone AFS98)

Specifications

Product Data

• Clone Name: AFS98
• Applications: Bl, FC, IHC, WB
• Reactivities: Mouse
• Host: Rat
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: This antibody was raised against CD115.
• Specificity: This antibody recognises mouse M-CSFR (CD115, CSF-1R) which is a membrane protein that influences tissue macrophage and osteoclast differentiation and proliferation.
  
  AFS98 has been widely used in various flow cytometric analyses to label CD115 antigen. For instance, one group used it to detect monocytes in a mouse blood sample (Buschor et al., 2019). Similarly, Huo and colleagues (2017) utilised this antibody to identify monocytes in mouse blood in order to assess whether myelopoiesis was not a cause of the increase in the monocytes number. This antibody has been also successfully used to deplete macrophages (Ho et al., 2016). Finally, it was also utilised in the immunofluorescence staining of tissue sections prepared from 4% paraformaldehyde-fixed and decalcified bones (Dong et al., 2016).
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: colony stimulating factor 1 receptor
• Database Link:
  Entrez Gene 12978 Mouse
  UniProt ID P09581
• Synonyms: C-FMS; CD115; CSF-1-R; CSFR; FIM2; FMS