CD53 Mouse Monoclonal Antibody [Clone ID: 161-2 (53/2)]

CAT#: TA386370

Recombinant Anti-CD53 (Clone 161-2 (53/2))

Specifications

Product Data

• Clone Name: 161-2 (53/2)
• Applications: FC, IF
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: This antibody was raised by immunizng mice with stimulated human leukocytes.
• Specificity: This antibody recognizes human CD53. It does not react with the baboon and horse antigen. Cd53 is a member of tetraspanin family and is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins.
  
  This antibody is recommended for the detection and analysis of CD53 via flow cytometry and immunofluorescence. Additionally, one group utilized this antibody for the ligation of the CD53 antigen while researching the potential involvement of tetraspanins (such as CD53) in tumor metastasis (Yunta et al., 2002). Furthermore, CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells, as it is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: CD53 molecule
• Database Link:
  Entrez Gene 963 Human
  UniProt ID P19397
• Synonyms: MOX44; tetraspanin-25; Tspan-25; TSPAN25