SFMBT1 Rabbit Monoclonal Antibody [Clone ID: RAB-C396]

CAT#: TA386473

Recombinant Anti-SFMBT1 (Clone RAB-C396)

Product Images

Flow cytometry using the Anti-SFMBT1 antibody RAB-C396 (Ab01714). Paraformaldehyde fixed A431 cells permeabilized with 0.5% Triton were stained with anti-unknown specificity antibody (Ab00178-23.0; isotype control, black line) or the rabbit IgG version of RAB-C396 (TA386473, blue line) at a dilution of 1:100 for 1h at RT. After washing, the bound antibody was detected using a goat anti-rabbit IgG AlexaFluor® 488 antibody at a dilution of 1:1000 and cells analyzed using a FACSCanto flow-cytometer.

Specifications

Product Data

• Clone Name: RAB-C396
• Applications: ChIP, ELISA
• Reactivities: Human
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Human Fab format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: This antibody was obtained by recombinant antibody (rAb) phage display recognizing SFMBT1 protein under non-denaturing conditions.
• Specificity: This antibody recognizes SFMBT1 (Scm-like with four MBT domains protein 1). It binds to a folded domain, amino acids 1-455. SFMBT1 is a histone-binding protein, which is part of various corepressor complexes. It mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription and plays a role during myogenesis.
  
  This antibody has been used and recommended for the following methods: ELISA; IP-MS; ChIP.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: Scm-like with four mbt domains 1
• Database Link:
  Entrez Gene 51460 Human
  UniProt ID Q9UHJ3
• Synonyms: DKFZp434L243; RU1; SFMBT