CD37 Rabbit Monoclonal Antibody [Clone ID: G28-1]

CAT#: TA386535

Recombinant Anti-CD37 (Clone G28-1)

Product Images

Flow cytometry using the Anti-CD37 antibody G28-1 (Ab02639). Paraformaldehyde fixed Daudi cells were stained with anti-unknown specificity antibody (Ab00178-23.0; isotype control, black line) or the rabbit IgG version of G28-1 (TA386535, blue line) at a dilution of 1:100 for 1h at RT. After washing, the bound antibody was detected using a goat anti-rabbit IgG AlexaFluor® 488 antibody at a dilution of 1:1000 and cells analyzed using a FACSCanto flow-cytometer.

Specifications

Product Data

• Clone Name: G28-1
• Reactivities: Human
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: This antibody was raised by immunizing mice with CD37.
• Specificity: This antibody recognises CD37, which is a cell surface protein, present mostly on mature B cells and B cell malignancies.
  
  G28-1 antibody was used to deplete normal and malignant B cells (Hayden-Ledbetter, unpublishesd). This antibody and antibody fragments derived therefrom have been used in the research and trials on the generation of novel immunotherapuetic agents, alternative to anti-CD20 therpaies (rituximab) (Robak and Robak, 2014).
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: CD37 molecule
• Database Link:
  Entrez Gene 951 Human
  UniProt ID P11049
• Synonyms: GP52-40; MGC120234; tetraspanin-26; Tspan-26; TSPAN26