Raptor (RPTOR) Rabbit Polyclonal Antibody

CAT#: TA392621

Raptor (phospho-Ser792) polyclonal antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic phosphopeptide derived from human Raptor around the phosphorylation site of Ser792.
• Specificity: A phospho specific peptide corresponding to residues surrounding Ser792 of human RPTOR
• Formulation: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Concentration: 1mg/ml
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
• Stability: 1 year
• Predicted Protein Size: ~ 150 kDa
• Gene Name: regulatory associated protein of MTOR complex 1
• Database Link:
  Entrez Gene 57521 Human
  UniProt ID Q8N122
• Background: Regulatory associated protein of FRAP, also designated Raptor, is a binding partner for mammalian target of rapamycin kinase (FRAP), and is essential for FRAP signalling in vivo. Raptor binding to FRAP is critical for FRAP-catalysed substrate phosphorylation of 4E-BP1. The raptor-FRAP complex is nutrient-sensitive and is important for a mechanism by which cells coordinate cell growth and size with changing environmental conditions. Raptor serves as a negative regulator of FRAP kinase activity under nutrient-deprived conditions and is an important component in the FRAP pathway. Raptor is highly expressed in skeletal muscle and to a lesser extent in brain, kidney, lung and placenta.
• Synonyms: KIAA1303; p150 target of rapamycin (TOR)-scaffold protein; RAPTOR; Raptor; Regulatory-associated protein of mTOR; RPTOR
• Note: For research use only, not for use in diagnostic procedure.