BMAL1 (ARNTL) Mouse Monoclonal Antibody [Clone ID: OTI1H6]

CAT#: TA501227

ARNTL mouse monoclonal antibody, clone OTI1H6 (formerly 1H6)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ARNTL (RC207870, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ARNTL. Positive lysates LY400474 (100ug) and LC400474 (20ug) can be purchased separately from OriGene.

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  Immunohistochemical staining of paraffin-embedded Human lung tissue within the normal limits using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

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  Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

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  Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

• Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

• Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

• Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

• Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-ARNTL mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min, TA501227)

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Specifications

Product Data

• Clone Name: OTI1H6
• Applications: IHC, WB
• Recommended Dilution: WB 1:4000, IHC 1:150
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human ARNTL(NP_001169) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68.5 kDa
• Gene Name: aryl hydrocarbon receptor nuclear translocator like
• Database Link:
  NP_001169
  Entrez Gene 11865 MouseEntrez Gene 29657 RatEntrez Gene 406 Human
  UniProt ID O00327
• Background: The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: bHLHe5; BMAL1; BMAL1c; JAP3; MOP3; PASD3; TIC

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Circadian rhythm - mammal