Destrin (DSTN) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1G8]

CAT#: TA502625AM

DSTN (Destrin) mouse monoclonal antibody, clone OTI1G8 (formerly 1G8), Biotinylated

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DSTN (RC203419, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DSTN. Positive lysates LY402051 (100ug) and LC402051 (20ug) can be purchased separately from OriGene.

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  Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-DSTN monoclonal antibody.

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  Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

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  Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

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  Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

• Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

• Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

• Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

• Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

• Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-DSTN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502625)

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Specifications

Product Data

• Clone Name: OTI1G8
• Applications: IHC, WB
• Recommended Dilution: WB 1:500~2000, IHC 1:150
• Reactivities: Human, Monkey, Mouse, Dog
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Full length human recombinant protein of human DSTN(NP_006861) produced in HEK293T cell.
• Formulation: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 0.5 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Biotin
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 18.3 kDa
• Gene Name: destrin, actin depolymerizing factor
• Database Link:
  NP_006861
  Entrez Gene 477147 DogEntrez Gene 695969 MonkeyEntrez Gene 11034 Human
  UniProt ID P60981
• Background: The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
• Synonyms: ACTDP; ADF; bA462D18.2; HEL32