AIPL1 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2B11]
CAT#: TA503695AM
AIPL1 mouse monoclonal antibody, clone OTI2B11 (formerly 2B11), Biotinylated
Other products for "AIPL1"
Specifications
Product Data | |
Clone Name | OTI2B11 |
Applications | FC, IF, WB |
Recommended Dilution | WB 1:500~2000, IF 1:100, FLOW 1:100 |
Reactivities | Human, Monkey, Mouse, Rat, Dog |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human AIPL1(NP_055151) produced in HEK293T cell. |
Formulation | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 43.7 kDa |
Gene Name | aryl hydrocarbon receptor interacting protein like 1 |
Database Link | |
Background | Leber congenital amaurosis (LCA) accounts for at least 5% of all inherited retinal disease and is the most severe inherited retinopathy with the earliest age of onset. Individuals affected with LCA are diagnosed at birth or in the first few months of life with severely impaired vision or blindness, nystagmus and an abnormal or flat electroretinogram. The photoreceptor/pineal -expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, was mapped within the LCA4 candidate region. The protein contains three tetratricopeptide motifs, consistent with nuclear transport or chaperone activity. AIPL1 mutations may cause approximately 20% of recessive LCA. [provided by RefSeq] |
Synonyms | AIPL2; LCA4 |
Reference Data | |
Protein Families | Druggable Genome |
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